G E Gibson Selected Research

Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)

3/2011	Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients.
6/2008	Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases.
6/2007	Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.
9/2000	Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype.
2/2000	The alpha-ketoglutarate dehydrogenase complex in neurodegeneration.
1/2000	Quantitative alpha-ketoglutarate dehydrogenase activity staining in brain sections and in cultured cells.

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G E Gibson Research Topics

Disease

5	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2008 - 01/2000
5	Alzheimer Disease (Alzheimer's Disease) 04/2001 - 01/2000
2	Huntington Disease (Huntington's Disease) 06/2008 - 07/2001
2	Parkinson Disease (Parkinson's Disease) 07/2003 - 04/2001
2	Inflammation (Inflammations) 04/2000 - 01/2000
1	Mental Disorders (Mental Disorder) 03/2011
1	Schizophrenia (Dementia Praecox) 03/2011
1	Due To LAD Deficiency Congenital Infantile Lactic Acidosis 06/2008
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2008
1	Thiamine Deficiency 06/2007
1	Multiple System Atrophy 04/2001
1	Amyloid Plaque 09/2000
1	Cognitive Dysfunction 09/2000
1	Neuroblastoma 01/2000

Drug/Important Bio-Agent (IBA)

7	EnzymesIBA 03/2011 - 01/2000
6	Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)IBA 03/2011 - 01/2000
4	Thiamine (Aneurin)FDA Link 06/2007 - 01/2000
2	Proteins (Proteins, Gene)FDA Link 06/2008 - 04/2000
1	Succinic Acid (Succinate)IBA 03/2011
1	Aconitate Hydratase (Aconitase)IBA 03/2011
1	Citrate (si)-Synthase (Synthase, Citrate)IBA 03/2011
1	Fumarate Hydratase (Fumarase)IBA 03/2011
1	Glucose (Dextrose)FDA LinkGeneric 03/2011
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 03/2011
1	Malate Dehydrogenase (Dehydrogenase, Malate)IBA 03/2011
1	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 03/2011
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 03/2011
1	Tricarboxylic AcidsIBA 03/2011
1	malonic acid (malonate)IBA 06/2008
1	Amyloid (Amyloid Fibrils)IBA 06/2008
1	Therapeutic UsesIBA 07/2001
1	Mitochondrial DNA (mtDNA)IBA 04/2001
1	Apolipoprotein E4IBA 09/2000
1	ApolipoproteinsIBA 09/2000
1	LipidsIBA 06/2000
1	IronIBA 04/2000
1	Free RadicalsIBA 04/2000
1	Oxidoreductases (Dehydrogenase)IBA 01/2000
1	AmproliumIBA 01/2000
1	Culture MediaIBA 01/2000
1	LipopolysaccharidesIBA 01/2000